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Last Updated: October 1, 2020

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Patent: 9,651,556

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Summary for Patent: 9,651,556
Title:Aptamers and diagnostic methods for detecting the EGF receptor
Abstract: The present invention provides aptamers that specifically bind to the EGF receptor in a sample, and diagnostic and analytical methods using those aptamers. In some embodiments, the aptamers include a 3\' cap. In some embodiments, the 3\' cap is an inverted deoxythymidine. In some embodiments the aptamers include a spacer and at least one moiety selected from the group consisting of binding pair member and a detectable label, wherein the spacer is attached to the 5\'-end of the aptamer and the moiety is attached the 5\' end of the spacer. In some embodiments the spacer is hexaethylene glycol. In some embodiments, the binding pair member biotin. In some embodiments the detectable label is a fluorophore.
Inventor(s): Bock; Chris (Denver, CO), Ayers; Deborah (Broomfield, CO), Nikrad; Malti P. (Boulder, CO), Gawande; Bharat Nathu (Lafayette, CO), Bertino; Jennifer C. (Arvada, CO), Sun; Weimin (Irvine, CA), Strom; Charles M. (San Clemente, CA), Park; Noh Jin (San Juan Capistrano, CA)
Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (Wilmington, DE) SOMALOGIC, INC. (Boulder, CO)
Application Number:14/369,398
Patent Claims:see list of patent claims

Details for Patent 9,651,556

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 003 2006-09-27   Start Trial QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (Wilmington, DE) SOMALOGIC, INC. (Boulder, CO) 2039-02-26 RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 002 2006-09-27   Start Trial QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (Wilmington, DE) SOMALOGIC, INC. (Boulder, CO) 2039-02-26 RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 001 2006-09-27   Start Trial QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (Wilmington, DE) SOMALOGIC, INC. (Boulder, CO) 2039-02-26 RX search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Start Trial QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (Wilmington, DE) SOMALOGIC, INC. (Boulder, CO) 2039-02-26 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

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Johnson and Johnson
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Colorcon

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