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Last Updated: October 29, 2020

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Patent: 9,650,444

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Summary for Patent: 9,650,444
Title:Anti-PDGFR-beta antibodies and uses thereof
Abstract: The present invention provides antibodies that bind to platelet derived growth factor receptor beta (PDGFR-beta) and methods of using the same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human PDGFR-beta with high affinity. The antibodies of the invention are useful for the treatment of diseases and disorders associated with PDGFR-beta signaling and/or PDGFR-beta cellular expression, such as ocular diseases, fibrotic diseases, vascular diseases and cancer.
Inventor(s): Wiegand; Stanley J. (Hopewell Junction, NY), Lobov; Ivan B. (New York, NY)
Assignee: Regeneron Pharmaceuticals, Inc. (Tarrytown, NY)
Application Number:14/992,589
Patent Claims:see list of patent claims

Details for Patent 9,650,444

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Regeneron Pharmaceuticals EYLEA aflibercept INJECTABLE; INJECTION 125387 001 2011-11-18   Start Trial Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) 2033-01-09 RX search
Genentech LUCENTIS ranibizumab INJECTABLE; INJECTION 125156 001 2006-06-30   Start Trial Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) 2033-01-09 RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) 2033-01-09 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) 2033-01-09 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 9,650,444

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