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Patent: 9,642,872
Summary for Patent: 9,642,872
| Title: | Treatment of B-cell lymphoma with microRNA |
| Abstract: | The invention relates to microRNA-34a and related microRNAs for use in the treatment of B-cell lymphoma. Likewise it relates to microRNA-34a for use in the preparation of a medicament for the treatment of B-cell lymphoma, and for a method of treatment of B-cell lymphoma comprising administering microRNA-34a. These claims are based on the observation that microRNA-34a shows strong anti-proliferative effects when overexpressed in diffuse large B-cell lymphoma (gDLBCL) cell lines, or when delivered intratumorally or systemically in xenograft models of DLBCL. |
| Inventor(s): | Craig; Vanessa (Zurich, CH), Mueller; Anne (Dubendorf, CH) |
| Assignee: | UNIVERSITY OF ZURICH (Zurich, CH) |
| Application Number: | 14/565,049 |
| Patent Claims: | see list of patent claims |
Details for Patent 9,642,872
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genentech | RITUXAN | rituximab | SOLUTION;INTRAVENOUS | 103705 | 001 | 1997-11-26 | Start Trial | UNIVERSITY OF ZURICH (Zurich, CH) | 2030-09-30 | RX | search | |
| Genentech | RITUXAN | rituximab | SOLUTION;INTRAVENOUS | 103705 | 002 | 1997-11-26 | Start Trial | UNIVERSITY OF ZURICH (Zurich, CH) | 2030-09-30 | RX | search | |
| Genentech Inc | RITUXAN HYCELA | rituximab; hyaluronidase (human recombinant) | SOLUTION;SUBCUTANEOUS | 761064 | 001 | 2017-06-22 | Start Trial | UNIVERSITY OF ZURICH (Zurich, CH) | 2030-09-30 | RX | Orphan | search |
| Genentech Inc | RITUXAN HYCELA | rituximab; hyaluronidase (human recombinant) | SOLUTION;SUBCUTANEOUS | 761064 | 002 | 2017-06-22 | Start Trial | UNIVERSITY OF ZURICH (Zurich, CH) | 2030-09-30 | RX | Orphan | search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 9,642,872
| Country | Patent Number | Publication Date |
|---|---|---|
| European Patent Office | 2622076 | Aug 07, 2013 |
| United States of America | 2013195858 | Aug 01, 2013 |
| United States of America | 2015322430 | Nov 12, 2015 |
| United States of America | 8933051 | Jan 13, 2015 |
| World Intellectual Property Organization (WIPO) | 2012041959 | Apr 05, 2012 |
| >Country | >Patent Number | >Publication Date |
