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Last Updated: July 11, 2020

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Patent: 9,592,303

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Summary for Patent: 9,592,303
Title:Enzyme-catalyzed synthesis of site-specific and stoichiometric biomolecule-polymer conjugates
Abstract: Methods for producing polypeptide-polymer conjugates include attachment of an initiator agent to a polypeptide specifically at the C-terminus of the polypeptide using a sortase enzyme and in situ polymerization of a polymer from the C-terminus. The polypeptide-polymer conjugates may have desirable pharmacological properties and may be used therapeutically.
Inventor(s): Chilkoti; Ashutosh (Durham, NC), Qi; Yizhi (Durham, NC)
Assignee: Duke University (Durham, NC)
Application Number:14/894,731
Patent Claims:see list of patent claims

Details for Patent 9,592,303

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial Duke University (Durham, NC) 2033-05-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 9,592,303

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