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Generated: September 18, 2019

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Patent: 9,592,303

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Summary for Patent: 9,592,303
Title:Enzyme-catalyzed synthesis of site-specific and stoichiometric biomolecule-polymer conjugates
Abstract: Methods for producing polypeptide-polymer conjugates include attachment of an initiator agent to a polypeptide specifically at the C-terminus of the polypeptide using a sortase enzyme and in situ polymerization of a polymer from the C-terminus. The polypeptide-polymer conjugates may have desirable pharmacological properties and may be used therapeutically.
Inventor(s): Chilkoti; Ashutosh (Durham, NC), Qi; Yizhi (Durham, NC)
Assignee: Duke University (Durham, NC)
Application Number:14/894,731
Patent Claims:see list of patent claims

Details for Patent 9,592,303

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Try a Free Trial Duke University (Durham, NC) 2033-05-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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International Patent Family for US Patent 9,592,303

Country Patent Number Publication Date
China 109152818 Jan 04, 2019
European Patent Office 3003342 Apr 13, 2016
European Patent Office 3003342 Mar 08, 2017
European Patent Office 3393500 Oct 31, 2018
United States of America 2016122451 May 05, 2016
United States of America 2017233714 Aug 17, 2017
United States of America 2017239363 Aug 24, 2017
>Country >Patent Number >Publication Date

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