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Generated: September 19, 2017

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Title:Gene expression markers of tumor resistance to HER2 inhibitor treatment
Abstract: The present invention concerns markers of resistance of HER2 expressing tumors to treatment with HER2 inhibitors, such as HER2 antibodies, including trastuzumab.
Inventor(s): Lee-Hoeflich; Si Tuen (Millbrae, CA), Stern; Howard (San Carlos, CA)
Assignee: Genentech, Inc. (South San Francisco, CA)
Application Number:12/806,419
Patent Claim Types:
see list of patent claims
Use; Device;

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Inventors Patent Expiration Status Orphan Source
Genentech
HERCEPTIN
trastuzumab
VIAL; INTRAVENOUS1037920011998-09-25► Subscribe Genentech, Inc. (South San Francisco, CA) Lee-Hoeflich; Si Tuen (Millbrae, CA), Stern; Howard (San Carlos, CA) ► SubscribeRXOrphansearch
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International Patent Family for Patent: ► Subscribe

Country Document Number Publication Date
Canada2690334Dec 18, 2008
Canada2690334Feb 14, 2017
Canada2917355Dec 18, 2008
Denmark2171090Jun 10, 2013
European Patent Office2171090Apr 03, 2013
European Patent Office2171090Apr 07, 2010
European Patent Office2592156Apr 20, 2016
European Patent Office2592156Aug 14, 2013
European Patent Office2592156May 15, 2013
Spain2417148Aug 06, 2013
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Serving 500+ biopharmaceutical companies globally:

Novartis
Boehringer Ingelheim
Express Scripts
Merck
Covington
Dow
Accenture
Queensland Health
Deloitte
Cipla

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