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Last Updated: July 11, 2020

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Patent: 9,550,997

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Summary for Patent: 9,550,997
Title:Screening of abundantly secreted proteins and their use as fusion partners for the production of recombinant proteins
Abstract: The present invention relates techniques for identifying suitable secretion fusion partner (SFP) for hyper-secretory production of recombinant proteins. The SFPs can be obtained from secretome analyzes. Recombinant proteins are produced in a fusion form with a secretion fusion partner (SFP) and can be separated from the SFP by in vitro protease treatment. SFPs of this invention greatly improve the secretion level of target proteins and peptides which are valuable for bio-pharmaceuticals and the bio-industry.
Inventor(s): Sohn; Jung-Hoon (Chungbuk, KR), Bae; Jung-Hoon (Daejeon, KR), Kim; Hyun-Jin (Ulsan, KR), Lim; Kwang-Mook (Daejeon, KR)
Assignee: Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR)
Application Number:12/631,449
Patent Claims:see list of patent claims

Details for Patent 9,550,997

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bpl ALBUMINEX albumin human SOLUTION 125644 1 2020-05-27   Start Trial Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR) 2028-12-04 search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR) 2028-12-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR) 2028-12-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR) 2028-12-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR) 2028-12-04 RX Orphan search
Kedrion S.p.a KEDBUMIN albumin (human) INJECTION, SOLUTION 125384 1 2011-09-15   Start Trial Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR) 2028-12-04 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial Korean Research Institute of Bioscience and Biotechnology (Daejeon, KR) 2028-12-04 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 9,550,997

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