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Last Updated: November 28, 2021

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Patent: 9,550,827

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Summary for Patent: 9,550,827
Title:Methods for ameliorating and preventing central nervous system inflammation
Abstract: The invention provides compositions and methods for ameliorating, treating, reversing or preventing pathology or inflammation in the central nervous system (CNS), or the brain, caused or mediated by NFkB, IL-6, IL-6-R, NADPH oxidase (Nox), and/or superoxide and/or hydrogen peroxide production by a NADPH oxidase, including for example ameliorating, treating, reversing or preventing schizophrenia, psychosis, delirium, e.g., post-operative delirium, drug-induced psychosis, psychotic features associated with frailty syndrome (FS), aging, depression, dementias; traumatic war neurosis, post traumatic stress disorder (PTSD) or post-traumatic stress syndrome (PTSS), Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig\'s Disease), and/or Multiple Sclerosis (MS). The invention also provides methods for purifying a C60 fullerene, C.sub.3 (tris malonic acid C60) or malonic acid derivatives.
Inventor(s): Dugan; Laura L. (Brentwood, TN), Behrens; Maria Margarita (Del Mar, CA), Ali; Sameh S. (San Diego, CA)
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, CA)
Application Number:12/681,743
Patent Claims:see list of patent claims

Details for Patent 9,550,827

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. ACTEMRA tocilizumab Injection 125276 2010-01-08 ⤷  Free Forever Trial 2027-10-19
Genentech, Inc. ACTEMRA tocilizumab Injection 125472 2013-10-21 ⤷  Free Forever Trial 2027-10-19
Genentech, Inc. ACTEMRA tocilizumab Injection 125472 2018-11-19 ⤷  Free Forever Trial 2027-10-19
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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