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Generated: September 16, 2019

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Patent: 9,546,369

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Summary for Patent: 9,546,369
Title:Multicistronic expression constructs
Abstract: Some aspects of this invention provide nucleic acid constructs for transgene expression. Some aspects of this invention provide multicistronic nucleic acid constructs, for example, comprising an expression cassette encoding a hairpin RNA and a reporter expression cassette. Some aspects of this invention provide nucleic acid constructs comprising two or more self-complementary nucleic acid sequences, for example, hairpin RNA encoding nucleic acid sequences and AAV inverse terminal repeats. Methods for the use of the constructs in therapy and research are also provided.
Inventor(s): Gao; Guangping (Westborough, MA), Xie; Jun (Shrewsbury, MA)
Assignee: University of Massachusetts (Boston, MA)
Application Number:13/642,747
Patent Claims:see list of patent claims

Details for Patent 9,546,369

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Try a Free Trial University of Massachusetts (Boston, MA) 2030-04-23 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Try a Free Trial University of Massachusetts (Boston, MA) 2030-04-23 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Try a Free Trial University of Massachusetts (Boston, MA) 2030-04-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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McKinsey

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