Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Cerilliant
Deloitte
Johnson and Johnson
Argus Health
Dow
Covington
Cipla
UBS
Citi
Moodys

Generated: October 19, 2017

Patent: ► Subscribe

Summary for Patent: ► Subscribe

Title:Optimized and defined method for isolation and preservation of precursor cells from human umbilical cord
Abstract: The present invention refers to an optimized and defined method for isolation and preservation of precursor cells from human umbilical cord. Besides being reproducible and 100% reliable, in terms of the number of samples processed, the method results in a high and defined number of precursor cells, being the majority obtained after a single adhesion and expansion/multiplication phase ex vivo (thus granting cell phenotype), in a shorter time frame than what was previously described in the state-of-the-art. With this method, it is possible to obtain, in 9 days, after direct freezing of a cell fraction, and after one expansion/multiplication phase ex vivo (end of P0) of the majority of the cells, about 8.6(.+-.0.1).times.10.sup.5 cells/gram of processed umbilical cord. In turn, the characteristics of the cells allow, for example, after 35 days, obtaining an average of 7.7.times.10.sup.15 cells, with precursor phenotype, from 100% of processed umbilical cord samples. The method, because it is simple, robust and 100% reliable, can be performed under good manufacturing practices (GMP) in laboratories dedicated to cell therapy in humans. Furthermore, the method has applications in the pharmaceutical, cosmetic and biotechnology areas.
Inventor(s): Ganchas Soares; Rita Isabel (Oeiras, PT), Baptista Coelho; Maria Constanca (Oeiras, PT), Silva Santos; Jorge Miguel (Oeiras, PT), Martins; Jose Paulo (Oeiras, PT), Basto; Vera Alexandra (Oeiras, PT), Estilita Monteiro Da Cruz; Pedro (Oeiras, PT), Soares Da Cruz; Helder Joaquim (Oeiras, PT)
Assignee: Laboratorio Medinfar-Produtos Farmaceuticos, S.A. (Amadora, PT)
Application Number:12/680,604
Patent Claim Types:
see list of patent claims
Use; Formulation;

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Inventors Patent Expiration Status Orphan Source
Advance Biofactures
SANTYL
collagenase
VIAL1019950011965-06-04► Subscribe Laboratorio Medinfar-Produtos Farmaceuticos, S.A. (Amadora, PT) Ganchas Soares; Rita Isabel (Oeiras, PT), Baptista Coelho; Maria Constanca (Oeiras, PT), Silva Santos; Jorge Miguel (Oeiras, PT), Martins; Jose Paulo (Oeiras, PT), Basto; Vera Alexandra (Oeiras, PT), Estilita Monteiro Da Cruz; Pedro (Oeiras, PT), Soares Da Cruz; Helder Joaquim (Oeiras, PT) ► SubscribeRXsearch
This preview shows a limited data set
Subscribe for full access, or try a Trial

Export unavailable in trial.
Subscribe for complete access.

Summary for Patent: ► Subscribe

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Portugal103843Oct 4, 2007
PCT Information
PCT FiledOctober 03, 2008PCT Application Number:PCT/IB2008/054067
PCT Publication Date:April 09, 2009PCT Publication Number: WO2009/044379

International Patent Family for Patent: ► Subscribe

Country Document Number Publication Date
This preview shows a limited data set
Subscribe for full access, or try a Trial

Export unavailable in trial.
Subscribe for complete access.


For more information try a trial or see the database preview and plans and pricing

Serving leading biopharmaceutical companies globally:

Farmers Insurance
US Army
QuintilesIMS
Novartis
Queensland Health
Merck
Colorcon
Deloitte
Johnson and Johnson
Federal Trade Commission

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

botpot