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Generated: September 22, 2019

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Patent: 9,539,245

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Summary for Patent: 9,539,245
Title:Combination of immunotherapies with activators of Tie-2
Abstract: The present invention relates to combination therapies comprising at least one activator of Tie-2 and immunotherapies that target immune checkpoints. Combination therapies of the disclosure can provide therapeutic effects not obtained with singly-administered immunotherapies. Combination therapies can be used to increase the therapeutic efficacy of an immunotherapy, to provide lower dosages of an immunotherapy being administered, to lower a toxicity of an immunotherapy, or to manage a side effect of an immunotherapy.
Inventor(s): Peters; Kevin (Cincinnati, OH)
Assignee: AERPIO THERAPEUTICS, INC. (Cincinnati, OH)
Application Number:14/819,871
Patent Claims:see list of patent claims

Details for Patent 9,539,245

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bristol Myers Squibb YERVOY ipilimumab INJECTABLE; INJECTION 125377 001 2011-03-25   Try a Free Trial AERPIO THERAPEUTICS, INC. (Cincinnati, OH) 2034-08-07 RX search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125527 001 2015-03-04   Try a Free Trial AERPIO THERAPEUTICS, INC. (Cincinnati, OH) 2034-08-07 RX search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125527 002 2015-03-04   Try a Free Trial AERPIO THERAPEUTICS, INC. (Cincinnati, OH) 2034-08-07 RX search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125554 001 2015-11-23   Try a Free Trial AERPIO THERAPEUTICS, INC. (Cincinnati, OH) 2034-08-07 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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