Patent: 9,532,989
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Summary for Patent: 9,532,989
| Title: | Oxadiazolo[3,2-A]pyrimidines and thiadiazolo[3,2-A]pyrimidines |
| Abstract: | The present invention relates to compounds of Formula P-I ##STR00001## where the variables (e.g. R.sub.1, Y, A, R.sub.1, R.sub.a, R.sub.a\', R.sub.b, R.sub.b\', R.sub.c, R.sub.c\', R.sub.d, R.sub.d\', R.sub.e, or R.sub.e\') and compositions useful for inhibiting and/or reducing platelet deposition, adhesion and/or aggregation. The present invention further relates to methods for the treatment or prophylaxis of thrombotic disorders, including stroke, myocardial infarction, unstable angina, peripheral vascular disease, abrupt closure following angioplasty or stent placement and thrombosis as a result of vascular surgery. |
| Inventor(s): | Coller; Barry S. (New York, NY), Thomas; Craig (Rockville, MD), Filizola; Marta (New York, NY), McCoy; Joshua (Portland, ME), Huang; Wenwei (Rockville, MD), Shen; Min (Boyds, MD) |
| Assignee: | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, DC) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY) THE ROCKEFELLER UNIVERSITY (New York, NY) |
| Application Number: | 14/730,707 |
| Patent Claims: | see list of patent claims |
Details for Patent 9,532,989
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Microbix Biosystems Inc. | KINLYTIC | urokinase | For Injection | 021846 | 01/16/1978 | ⤷ Try a Trial | 2030-07-16 |
| Genentech, Inc. | ACTIVASE | alteplase | For Injection | 103172 | 11/13/1987 | ⤷ Try a Trial | 2030-07-16 |
| Genentech, Inc. | CATHFLO ACTIVASE | alteplase | For Injection | 103172 | 09/04/2001 | ⤷ Try a Trial | 2030-07-16 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
