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Last Updated: April 25, 2024

Patent: 9,526,791

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Summary for Patent: 9,526,791

Title:	Weakly acidic pH-responsive peptide and liposome containing same
Abstract:	A problem to be solved by the present invention is to provide a peptide compound for producing a drug delivery carrier capable of releasing a target substance in a weakly acidic pH environment. The present invention provides a peptide compound comprising a hydrophilic amino acid block and a hydrophobic amino acid block; [1] the peptide compound containing 24 to 36 amino acids in total; [2] the hydrophilic amino acid block containing 4 to 10 amino acids in total and having an average hydropathy index of -3.0 to -1.0; and [3] the hydrophobic amino acid block containing 20 to 32 amino acids in total, containing one or more His residues, and having an average hydropathy index of 1.0 to 2.5.
Inventor(s):	Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP)
Assignee:	Taiho Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:	14/430,723
Patent Claims:	see list of patent claims

Details for Patent 9,526,791

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Amgen, Inc.	NEUPOGEN	filgrastim	Injection	103353	02/20/1991	⤷ Try a Trial	2032-10-22
Amgen, Inc.	NEUPOGEN	filgrastim	Injection	103353	06/28/2000	⤷ Try a Trial	2032-10-22
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	11/26/1997	⤷ Try a Trial	2032-10-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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