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Last Updated: November 28, 2021

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Patent: 9,523,691

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Summary for Patent: 9,523,691
Title:Use of the olfactomedin-4 protein (OLFM4) in colorectal cancer diagnosis
Abstract: The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting the responds to a chemotherapeutic agent of a subject suffering from a colorectal cancer: according to the present invention, the by determining the OLFM4 levels. According to the present invention, the response can be predicted by determining the OLFM4 levels. This result in turn permits the design or the adaptation of a treatment of the said subject with the said chemotherapeutic agent.
Inventor(s): Guette; Catherine (La Possonniere, FR), Coqueret; Olivier (Angers, FR), Barre; Benjamin (Brain sur Longuenee, FR), Gamelin; Erick (Paris, FR)
Assignee: INSTITUT DE CANCEROLOGIE DE L\'OUEST (Angers, FR)
Application Number:14/002,225
Patent Claims:see list of patent claims

Details for Patent 9,523,691

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company ERBITUX cetuximab Injection 125084 2004-02-12 ⤷  Free Forever Trial 2039-02-26
Eli Lilly And Company ERBITUX cetuximab Injection 125084 2007-03-28 ⤷  Free Forever Trial 2039-02-26
Amgen, Inc. VECTIBIX panitumumab Injection 125147 2006-09-27 ⤷  Free Forever Trial 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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