Patent: 9,498,539
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Summary for Patent: 9,498,539
Title: | Affinity-based controlled release system |
Abstract: | Prolonged or extended release of bioactive protein is achieved using an affinity-based approach which exploits the specific binding of Src homology 3 (SH3) domain with short proline-rich peptides. Specifically, methylcellulose was modified with SH3-binding peptides (MC-peptide) with either a weak affinity or strong affinity for SH3. Controlled release of chondroitinase ABC (ChABC) is also described. |
Inventor(s): | Shoichet; Molly Sandra (Toronto, CA), Vulic; Katarina (Oakville, CA) |
Assignee: | |
Application Number: | 13/728,946 |
Patent Claims: | see list of patent claims |
Details for Patent 9,498,539
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Emd Serono, Inc. | PERGONAL | menotropins | For Injection | 017646 | 08/22/1975 | ⤷ Try a Trial | 2040-03-30 |
Emd Serono, Inc. | PERGONAL | menotropins | For Injection | 017646 | 05/20/1985 | ⤷ Try a Trial | 2040-03-30 |
Organon Usa Inc., A Subsidiary Of Merck & Co., Inc. | HUMEGON | menotropins | For Injection | 020328 | 09/01/1994 | ⤷ Try a Trial | 2040-03-30 |
Ferring Pharmaceuticals Inc. | REPRONEX | menotropins | For Injection | 021047 | 08/27/1999 | ⤷ Try a Trial | 2040-03-30 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |