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Last Updated: December 7, 2021

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Patent: 9,481,896

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Summary for Patent: 9,481,896
Title:Stem cell gene targeting
Abstract: The invention provides a method for generating a transgenic eukaryotic cell population having a modified human Rosa26 locus, which method includes introducing a functional DNA sequence into the human Rosa26 locus of starting eukaryotic cells. Also provided are targeting vectors useful in the method, as well as a cell population and a transgenic non-human animal comprising a modified human Rosa26 locus. Finally, the invention provides an isolated DNA sequence corresponding to the human Rosa26 locus.
Inventor(s): Keller; Gordon (Toronto, CA), Irion; Stefan (Toronto, CA), Luche; Herve (Ulm, DE), Gadue; Paul (New York, NY), Fehling; Hans J. (Ulm, DE)
Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY)
Application Number:14/717,472
Patent Claims:see list of patent claims

Details for Patent 9,481,896

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2027-01-19
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2027-01-19
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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