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Generated: July 16, 2019

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Patent: 9,480,745

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Summary for Patent: 9,480,745
Title:Targeted treatment of anerobic cancer
Abstract: The present invention relates to a pharmaceutical cocktail and methods of treatment involving said cocktail, in particular, a combination of effective amounts of a carbonic anhydrase inhibitor, in combination with effective amounts of an angiogenesis inhibitor, including a vascular endothelial growth factor (VEGF) inhibitor such as bevacizumab for the treatment of cancer. In other embodiments, it relates to compositions and methods of treating cancer involving effective amounts of a carbonic anhydrase inhibitor. Pharmaceutical compositions and methods of treating cancer (eliminating the tumor, shrinking the tumor, prolonging the life of the patient, increasing quality of life by decreasing the grade of adverse events seen with other cancer treatments, and/or preventing/reducing the likelihood of the tumor\'s metastases) are additional aspects of the present invention. In addition, the present invention may be used to favorably impact the therapeutic result of patients who have not responded to alternative, traditional anti-cancer therapy.
Inventor(s): Haaga; John R. (Chagrin Falls, OH), Haaga; Rebecca (Chagrin Falls, OH)
Assignee: University Hospitals Cleveland Medical Center (Cleveland, OH)
Application Number:14/379,206
Patent Claims:see list of patent claims

Details for Patent 9,480,745

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Try a Free Trial University Hospitals Cleveland Medical Center (Cleveland, OH) ➤ Try a Free Trial RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26 ➤ Try a Free Trial University Hospitals Cleveland Medical Center (Cleveland, OH) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 9,480,745

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 2013130354 Sep 06, 2013
United States of America 2016000913 Jan 07, 2016
United States of America 2017056350 Mar 02, 2017
United States of America 9918950 Mar 20, 2018
European Patent Office 2819706 Aug 12, 2015
European Patent Office 2819706 Jan 07, 2015
Canada 2866079 Sep 06, 2013
Country Patent Number Publication Date

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Serving hundreds of leading biopharmaceutical companies globally:

Merck
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Chubb
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Federal Trade Commission
Colorcon

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