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Last Updated: August 4, 2020

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Patent: 9,475,812

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Summary for Patent: 9,475,812
Title:Pyridonaphthyridine type dual PI3K and mTOR inhibitor and its preparation and use
Abstract: The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease. ##STR00001##
Inventor(s): Wu; Frank (Jinan, CN), Zhang; Yan (Jinan, CN)
Assignee: Xuanzhu Pharma Co., Ltd. (Jinan, CN)
Application Number:14/123,934
Patent Claims:see list of patent claims

Details for Patent 9,475,812

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Xuanzhu Pharma Co., Ltd. (Jinan, CN) 2031-06-04 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Xuanzhu Pharma Co., Ltd. (Jinan, CN) 2031-06-04 RX Orphan search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial Xuanzhu Pharma Co., Ltd. (Jinan, CN) 2031-06-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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