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Last Updated: February 25, 2020

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Patent: 9,469,689

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Summary for Patent: 9,469,689
Title:Therapeutic DLL4 binding proteins
Abstract: DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.
Inventor(s): Chen; Ming-Jiu (Shrewsbury, MA), Hsieh; Chung-Ming (Newton, MA), Gu; Jijie (Shrewsbury, MA), Morgan-Lappe; Susan E. (Riverwoods, IL), Li; Yingchun (Buffalo Grove, IL)
Assignee: AbbVie Inc. (North Chicago, IL)
Application Number:14/798,849
Patent Claims:see list of patent claims

Details for Patent 9,469,689

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Regeneron Pharmaceuticals EYLEA aflibercept INJECTABLE; INJECTION 125387 001 2011-11-18   Start Trial AbbVie Inc. (North Chicago, IL) 2030-03-02 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Express Scripts
Johnson and Johnson

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