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Last Updated: December 3, 2021

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Patent: 9,469,689

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Summary for Patent: 9,469,689
Title:Therapeutic DLL4 binding proteins
Abstract: DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.
Inventor(s): Chen; Ming-Jiu (Shrewsbury, MA), Hsieh; Chung-Ming (Newton, MA), Gu; Jijie (Shrewsbury, MA), Morgan-Lappe; Susan E. (Riverwoods, IL), Li; Yingchun (Buffalo Grove, IL)
Assignee: AbbVie Inc. (North Chicago, IL)
Application Number:14/798,849
Patent Claims:see list of patent claims

Details for Patent 9,469,689

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Regeneron Pharmaceuticals, Inc. EYLEA aflibercept Injection 125387 2011-11-18 ⤷  Try it Free 2030-03-02
Regeneron Pharmaceuticals, Inc. EYLEA aflibercept Injection 125387 2018-08-16 ⤷  Try it Free 2030-03-02
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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