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Generated: July 20, 2019

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Patent: 9,469,689

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Summary for Patent: 9,469,689
Title:Therapeutic DLL4 binding proteins
Abstract: DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.
Inventor(s): Chen; Ming-Jiu (Shrewsbury, MA), Hsieh; Chung-Ming (Newton, MA), Gu; Jijie (Shrewsbury, MA), Morgan-Lappe; Susan E. (Riverwoods, IL), Li; Yingchun (Buffalo Grove, IL)
Assignee: AbbVie Inc. (North Chicago, IL)
Application Number:14/798,849
Patent Claims:see list of patent claims

Details for Patent 9,469,689

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Regeneron Pharmaceuticals EYLEA aflibercept INJECTABLE; INJECTION 125387 001 2011-11-18 ➤ Try a Free Trial AbbVie Inc. (North Chicago, IL) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 9,469,689

Country Patent Number Publication Date
South Africa 201206552 May 29, 2013
World Intellectual Property Organization (WIPO) 2011109298 Nov 24, 2011
World Intellectual Property Organization (WIPO) 2011109298 Sep 09, 2011
Uruguay 33254 Sep 30, 2011
United States of America 2011217237 Sep 08, 2011
United States of America 2016031986 Feb 04, 2016
United States of America 9115195 Aug 25, 2015
Country Patent Number Publication Date

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