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Mallinckrodt
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Generated: July 23, 2019

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Patent: 9,421,194

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Summary for Patent: 9,421,194
Title:Lung targeting dual drug delivery system
Abstract: The American Cancer Society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the United States of which 219,440 would be lung and bronchus related. The standard treatments for NSCLC include surgery, chemotherapy, radiation, laser and photodynamic therapy, all with various success rates depending on the stage of the cancer. National Cancer Institute assesses, however, that results of standard treatment are generally poor with only a 15 percent 5-year survival rate for combined cancer stages. Challenges facing the current chemotherapy drugs include excessive toxicity to healthy tissues and limited ability to prevent metastases. A dual drug delivery system described herein selectively targets the lung to deliver anti-cancer drugs and inhibit the formation of metastases.
Inventor(s): Prud\'homme; Robert K. (Lawrenceville, NJ), Sinko; Patrick J. (Annandale, NJ), Stone; Howard A. (Princeton, NJ), Pinkerton; Nathalie M. (Ottawa Hills, OH), Shi; Lei (Shanghai, CN), Wan; Jiandi (Lawrenceville, NJ), Ibrahim; Sherif (Old Bridge, NJ), Gao; Dayuan (East Brunswick, NJ)
Assignee: Rutgers, The State University of New Jersey (New Brunswick, NJ) The Trustees of Princeton University (Princeton, NJ)
Application Number:13/080,371
Patent Claims:see list of patent claims

Details for Patent 9,421,194

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up Rutgers, The State University of New Jersey (New Brunswick, NJ) The Trustees of Princeton University (Princeton, NJ) ➤ Sign Up RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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US Department of Justice
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Julphar
Baxter
Teva
Express Scripts

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