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Last Updated: September 27, 2020

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Patent: 9,415,103

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Summary for Patent: 9,415,103
Title:Combination therapy to prevent DCIS formation and progression to breast cancer
Abstract: A method of treating a ductal carcinoma in situ (DCIS) lesion in a subject in need thereof is disclosed. The method comprises administering to the subject a therapeutically effective amount of a first agent capable of down-regulating activity and/or expression of at least one component participating in a NOTCH pathway, and a second agent capable of down-regulating an activity and/or expression of HER2, thereby treating the DCIS lesion.
Inventor(s): Yarden; Yosef (Rehovot, IL), Chaluvally-Raghavan; Pradeep (Rehovot, IL)
Assignee: Yeda Research and Development Co. Ltd. (Rehovot, IL)
Application Number:14/125,588
Patent Claims:see list of patent claims

Details for Patent 9,415,103

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial Yeda Research and Development Co. Ltd. (Rehovot, IL) 2031-06-14 RX Orphan search
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial Yeda Research and Development Co. Ltd. (Rehovot, IL) 2031-06-14 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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