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Generated: September 19, 2019

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Patent: 9,388,243

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Summary for Patent: 9,388,243
Title:Method of target membrane protein depletion
Abstract: A method of target membrane protein depletion comprising treating a cell with a dual binding molecule comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the cell comprises a cell membrane, and the driver membrane protein and target membrane protein are associated with the cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and compositions.
Inventor(s): Cheong; Kwang Ho (Seoul, KR), Lee; Seung Hyun (Suwon-si, KR), Cho; Mi Young (Seoul, KR), Koh; Young Jun (Yongin-si, KR), Powei; Lin (Hwaseong-si, KR), Yi; Christina (Seongnam-si, KR), Hwang; Jae Woong (Seoul, KR)
Assignee: SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR)
Application Number:14/290,447
Patent Claims:see list of patent claims

Details for Patent 9,388,243

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR) 2033-05-29 RX Orphan search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18 ➤ Sign Up SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR) 2033-05-29 RX Orphan search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 001 2006-09-27 ➤ Sign Up SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR) 2033-05-29 RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 002 2006-09-27 ➤ Sign Up SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR) 2033-05-29 RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 003 2006-09-27 ➤ Sign Up SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR) 2033-05-29 RX search
Genentech PERJETA pertuzumab VIAL; SINGLE-USE 125409 001 2012-06-08 ➤ Sign Up SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR) 2033-05-29 RX search
Eli Lilly And Co CYRAMZA ramucirumab INJECTABLE;INJECTION 125477 001 2014-04-21 ➤ Sign Up SAMSUNG ELECTRONICS CO., LTD. (Suwon-Si, KR) 2033-05-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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