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Last Updated: August 11, 2020

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Patent: 9,381,243

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Summary for Patent: 9,381,243
Title:Methods of identifying critically ill patients at increased risk of development of organ failure and compounds for the treatment hereof
Abstract: The present invention relates to compounds for treatment that protects the endothelium, prevents pathologic thrombus formation in the microcirculation and preserves platelet number and function and thus may be related to minimizing or preventing development of organ failure, including multiple organ failure (MOF), and, hence, death in critically ill patients by administration of agent(s) limiting the platelets ability to aggregate and form clots and/or by agents modulating/preserving endothelial integrity and/or by agent(s) increasing the rate of thrombus lysis, and Another aspect of the invention related to by a cell-based whole blood viscoelastical haemostatic assay identifying critically ill patients at increased risk of development of organ failure, including multiple organ failure (MOF) and death.
Inventor(s): Johansson; Par (Dosjebro, SE), Ostrowski; Sisse Rye (Gentofte, DK)
Assignee: Rigshospitalet (Kobenhavn O, DK)
Application Number:14/329,350
Patent Claims:see list of patent claims

Details for Patent 9,381,243

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Start Trial Rigshospitalet (Kobenhavn O, DK) 2028-12-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 9,381,243

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