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Generated: July 21, 2019

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Patent: 9,375,496

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Summary for Patent: 9,375,496
Title:Halogenated compounds for cancer imaging and treatment and methods for their use
Abstract: Compounds having a structure of Formula I: ##STR00001## or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, X.sup.1, X.sup.2, X.sup.3 and X.sup.4 are as defined herein, and wherein the compound comprises at least one F, Cl, Br, I or .sup.123I moiety, are provided. Uses of such compounds for imaging diagnostics in cancer and therapeutics methods for treatment of subjects in need thereof, including prostate cancer as well as methods and intermediates for preparing such compounds are also provided.
Inventor(s): Andersen; Raymond John (Vancouver, CA), Banuelos; Carmen Adriana (Richmond, CA), Garcia Fernandez; Javier (Colunga, ES), Imamura; Yusuke (Chiba, JP), Kunzhong; Jian (Vancouver, CA), Mawji; Nasrin R. (Burnaby, CA), Sadar; Marianne Dorothy (West Vancouver, CA), Wang; Jun (Surrey, CA), Tien; Amy (Hsing Chen) (Vancouver, CA)
Assignee: British Columbia Cancer Agency Branch (CA) The University of British Columbia (CA)
Application Number:14/481,727
Patent Claims:see list of patent claims

Details for Patent 9,375,496

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Bristol Myers Squibb YERVOY ipilimumab INJECTABLE; INJECTION 125377 001 2011-03-25 ➤ Sign Up British Columbia Cancer Agency Branch (CA) The University of British Columbia (CA) ➤ Sign Up RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Sign Up British Columbia Cancer Agency Branch (CA) The University of British Columbia (CA) ➤ Sign Up RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26 ➤ Sign Up British Columbia Cancer Agency Branch (CA) The University of British Columbia (CA) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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