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Last Updated: September 28, 2020

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Patent: 9,371,527

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Summary for Patent: 9,371,527
Title:Compositions and methods related to protein displacement therapy for myotonic distrophy
Abstract: Disclosed are compositions and methods related to the interaction of polyCUG and polyCCUG repeat RNA and proteins that bind to these repetitive RNA sequences. Also disclosed are methods of treating DM1 or DM2 comprising inhibiting the interaction of poly(CUG).sup.exp or poly(CCUG).sup.exp RNA with muscleblind proteins, or by causing improvement of spliceopathy in myotonic dystrophy.
Inventor(s): Thornton; Charles A. (Rochester, NY), Wheeler; Thurman (Rochester, NY), Sobczak; Krzysztof (Poznan, PL), Osborne; Robert (Essex, GB), Miller; Jill (Rockport, NY), Swanson; Maurice Scott (Gainsville, FL)
Assignee: University of Rochester (Rochester, NY)
Application Number:14/297,137
Patent Claims:see list of patent claims

Details for Patent 9,371,527

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial University of Rochester (Rochester, NY) 2026-09-21 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial University of Rochester (Rochester, NY) 2026-09-21 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial University of Rochester (Rochester, NY) 2026-09-21 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

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Moodys
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Baxter
McKesson

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