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Generated: September 19, 2019

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Patent: 9,359,347

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Summary for Patent: 9,359,347
Title:Inhibitors of Akt/PKB with anti-tumor activity
Abstract: The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of Akt proteins. The subject invention also concerns methods for inhibiting or killing a cancer cell or other cell in which expression of an Akt protein is elevated or constitutively active, comprising contacting the cell with an effective amount of a compound of formula I. The subject invention also concerns methods for treating cancer or a tumor in a person or animal comprising administering an effective amount of a compound of formula I to the person or animal.
Inventor(s): Cheng; Jin Q. (Tampa, FL), Sun; Mei (Tampa, FL), Sebti; Said M. (Tampa, FL)
Assignee: University of South Florida (Tampa, FL)
Application Number:13/476,098
Patent Claims:see list of patent claims

Details for Patent 9,359,347

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26 ➤ Sign Up University of South Florida (Tampa, FL) 2027-07-12 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up University of South Florida (Tampa, FL) 2027-07-12 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07 ➤ Sign Up University of South Florida (Tampa, FL) 2027-07-12 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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