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Last Updated: November 27, 2021

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Patent: 9,353,366

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Summary for Patent: 9,353,366
Title:Asparaginase and treating diseases associated with asparagine dependence
Abstract: Disclosed herein are polypeptides which exhibit asparaginase activity and little to no glutaminase activity. The polypeptides have sequences which correspond to W. succinogenes asparaginase, but have an amino acid residue other than proline at amino acid position 121. The polypeptides exhibit higher kinetic rates of asparaginase activity to glutaminase activity as compared to W. succinogenes asparaginase and Elspar.RTM., an E. coli asparaginase.
Inventor(s): Durden; Donald L. (La Jolla, CA)
Assignee: Children\'s Hospital Los Angeles (Los Angeles, CA)
Application Number:14/706,132
Patent Claims:see list of patent claims

Details for Patent 9,353,366

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 1978-01-10 ⤷  Try it Free 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Johnson and Johnson

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