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Last Updated: December 8, 2021

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Patent: 9,346,769

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Summary for Patent: 9,346,769
Title:Tetrazolones as inhibitors of fatty acid synthase
Abstract: Provided herein are tetrazolone FASN inhibitors of the formula (I): ##STR00001## or a pharmaceutically acceptable form thereof; wherein the variables R.sup.A, R.sup.B and R.sup.C are defined herein. Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.
Inventor(s): Bahadoor; Adilah (Stittsville, CA), Castro; Alfredo C. (Winchester, MA), Chan; Lawrence K. (Brookline, MA), Keaney; Gregg F. (Lexington, MA), Nevalainen; Marta (Weymouth, MA), Nevalainen; Vesa (Weymouth, MA), Peluso; Stephane (Brookline, MA), Snyder; Daniel A. (Somerville, MA), Tibbitts; Thomas T. (Westford, MA)
Assignee: Infinity Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:13/975,236
Patent Claims:see list of patent claims

Details for Patent 9,346,769

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2030-05-05
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2030-05-05
Hoffmann-la Roche Inc. ROFERON-A interferon alfa-2a For Injection 103145 1986-06-04 ⤷  Free Forever Trial 2030-05-05
Kadmon Pharmaceuticals Llc INFERGEN interferon alfacon-1 Injection 103663 1997-10-06 ⤷  Free Forever Trial 2030-05-05
Horizon Therapeutics Ireland Dac ACTIMMUNE interferon gamma-1b Injection 103836 1999-02-25 ⤷  Free Forever Trial 2030-05-05
Merck Sharp & Dohme Corp. PEGINTRON peginterferon alfa-2b Injection 103949 2001-01-19 ⤷  Free Forever Trial 2030-05-05
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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