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Generated: August 18, 2019

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Patent: 9,303,044

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Summary for Patent: 9,303,044
Title:7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-A]pyrimidin-5-ones for the treatment of thrombotic disorders
Abstract: The present invention relates to compounds and compositions of Formula P useful for inhibiting and/or reducing platelet deposition, adhesion and/or aggregation. The definitions of variables A, B, R.sub.2, R.sub.3, R.sub.4, R.sub.a, R.sub.a\', R.sub.b, R.sub.b\', R.sub.c, R.sub.d, R.sub.d\', R.sub.e, and R.sub.e\' are provided in the disclosure. The present invention further relates to methods for the treatment or prophylaxis of thrombotic disorders, including stroke, myocardial infarction, unstable angina, peripheral vascular disease, abrupt closure following angioplasty or stent placement and thrombosis as a result of vascular surgery.
Inventor(s): Coller; Barry S. (New York, NY), Thomas; Craig (Rockville, MD), Filizola; Marta (New York, NY), McCoy; Joshua (Portland, ME), Huang; Wenwei (Rockville, MD), Shen; Min (Boyds, MD), Jiang; Jian-Kang (Columbia, MD)
Assignee: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, DC) THE ROCKEFELLER UNIVERSITY (New York, NY) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY)
Application Number:14/372,488
Patent Claims:see list of patent claims

Details for Patent 9,303,044

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech TNKASE tenecteplase VIAL 103909 001 2000-06-02 ➤ Sign Up THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, DC) THE ROCKEFELLER UNIVERSITY (New York, NY) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY) 2033-01-16 RX search
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22 ➤ Sign Up THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, DC) THE ROCKEFELLER UNIVERSITY (New York, NY) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY) 2033-01-16 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13 ➤ Sign Up THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, DC) THE ROCKEFELLER UNIVERSITY (New York, NY) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY) 2033-01-16 RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source

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