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Generated: July 19, 2019

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Patent: 9,249,182

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Summary for Patent: 9,249,182
Title:Purification of antibodies using hydrophobic interaction chromatography
Abstract: Disclosed herein are compositions and methods for purifying antibody products from a sample matrix. In particular, the present invention relates to compositions and methods for purifying antibody products employing hydrophobic interaction chromatography media. In certain embodiments, the invention provides a method for reducing process-related impurities (e.g., host cell proteins), as well as product-related substances, including molecular weight variants (e.g., aggregates and fragments of the antibody product).
Inventor(s): Herigstad; Matthew Omon (Charlestown, MA), Rich; Linda E. (Worcester, MA), Lu; Stephen Ming-teh (Worcester, MA), Ramasubramanyan; Natarajan (Westborough, MA)
Assignee: AbbVie, Inc. (North Chicago, IL)
Application Number:13/831,181
Patent Claims:see list of patent claims

Details for Patent 9,249,182

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31 ➤ Sign Up AbbVie, Inc. (North Chicago, IL) ➤ Sign Up RX search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31 ➤ Sign Up AbbVie, Inc. (North Chicago, IL) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 9,249,182

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 2013176754 May 01, 2014
World Intellectual Property Organization (WIPO) 2013176754 Nov 28, 2013
World Intellectual Property Organization (WIPO) 2014143185 Sep 18, 2014
United States of America 2014072585 Mar 13, 2014
United States of America 2016115193 Apr 28, 2016
Country Patent Number Publication Date

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Serving hundreds of leading biopharmaceutical companies globally:

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Cantor Fitzgerald
Chinese Patent Office

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