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Patent: 9,248,172
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Summary for Patent: 9,248,172
| Title: | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
| Abstract: | The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an .alpha.-2-macroglobulin (.alpha.2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an .alpha.2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules or .alpha.2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality. |
| Inventor(s): | Srivastava; Pramod K. (Avon, CT), Li; Zihai (Mount Pleasant, SC) |
| Assignee: | University of Connecticut Health Center (Farmington, CT) |
| Application Number: | 14/043,666 |
| Patent Claims: | see list of patent claims |
Details for Patent 9,248,172
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genentech | AVASTIN | bevacizumab | VIAL; INTRAVENOUS | 125085 | 002 | 2004-02-26 | Start Trial | University of Connecticut Health Center (Farmington, CT) | 2022-04-25 | RX | search | |
| Genentech | AVASTIN | bevacizumab | VIAL; INTRAVENOUS | 125085 | 001 | 2004-02-26 | Start Trial | University of Connecticut Health Center (Farmington, CT) | 2022-04-25 | RX | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 9,248,172
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 03090686 | Start Trial |
| United States of America | 2003203846 | Start Trial |
| United States of America | 2006079458 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
