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Last Updated: December 7, 2021

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Patent: 9,241,931

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Summary for Patent: 9,241,931
Title:Compound useful for the treatment of degenerative and inflammatory diseases
Abstract: A pyrazolopyridine compound according to Formula I, able to inhibit JAK is disclosed, as well as pharmaceutically acceptable salts, a solvate thereof, solvates of the pharmaceutically acceptable salts and biologically active metabolites thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the treatment or prophylaxis of a variety of conditions in mammals including humans, and particularly, such conditions as may be associated with aberrant JAK activity, including by way of non-limiting example, allergy, inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6. ##STR00001##
Inventor(s): Menet; Christel Jeanne Marie (Mechelen, BE), Hodges; Alastair James (Essex, GB), Vater; Huw David (Essex, GB)
Assignee: GALAPAGOS NV (Mechelen, BE)
Application Number:14/457,071
Patent Claims:see list of patent claims

Details for Patent 9,241,931

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. RITUXAN rituximab Injection 103705 1997-11-26 ⤷  Try it Free 2031-04-28
Idec Pharmaceuticals Corp. RITUXAN rituximab Injection 103737 2002-02-19 ⤷  Try it Free 2031-04-28
Janssen Biotech, Inc. REMICADE infliximab For Injection 103772 1998-08-24 ⤷  Try it Free 2031-04-28
Abbvie Inc. HUMIRA adalimumab Injection 125057 2002-12-31 ⤷  Try it Free 2031-04-28
Abbvie Inc. HUMIRA adalimumab Injection 125057 2008-02-21 ⤷  Try it Free 2031-04-28
Abbvie Inc. HUMIRA adalimumab Injection 125057 2013-04-24 ⤷  Try it Free 2031-04-28
Abbvie Inc. HUMIRA adalimumab Injection 125057 2014-09-23 ⤷  Try it Free 2031-04-28
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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