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Last Updated: July 11, 2020

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Patent: 9,237,945

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Summary for Patent: 9,237,945
Title:Bioerodible wraps and uses therefor
Abstract: A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
Inventor(s): El-Kurdl; Mohammed S. (Pittsburgh, PA), Hong; Yi (Pittsburgh, PA), Soletti; Lorenzo (Pittsburgh, PA), Stankus; John J. (Campbell, CA), Vorp; David A. (Pittsburgh, PA), Wagner; William R. (Pittsburgh, PA)
Assignee: University of Pittsburgh--Of the Commonwealth System of Higher Education (Pittsburgh, PA)
Application Number:12/022,430
Patent Claims:see list of patent claims

Details for Patent 9,237,945

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech LUCENTIS ranibizumab INJECTABLE; INJECTION 125156 001 2006-06-30   Start Trial University of Pittsburgh--Of the Commonwealth System of Higher Education (Pittsburgh, PA) 2027-01-30 RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial University of Pittsburgh--Of the Commonwealth System of Higher Education (Pittsburgh, PA) 2027-01-30 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial University of Pittsburgh--Of the Commonwealth System of Higher Education (Pittsburgh, PA) 2027-01-30 RX Orphan search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial University of Pittsburgh--Of the Commonwealth System of Higher Education (Pittsburgh, PA) 2027-01-30 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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