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Generated: September 18, 2019

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Patent: 9,222,104

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Summary for Patent: 9,222,104
Title:Method for creating broad-spectrum resistance to fungi in transgenic plants
Abstract: The present invention relates to the creation of broad-spectrum resistance in transgenic plants by inserting inhibitory nucleic acid sequences inhibiting the expression of fungal genes. The nucleic acid sequences of genes which are crucial to development, growth and profilation of fungi, i.e. sequences of genes with an essential function in fungi, are often conserved and/or have a high sequence identity. Regions having a particularly high sequence identity between various fungi are used in order to produce inhibitory gene constructs, e.g. on basis of antisense, siRNA, shRNA, ribozyme technology and other technologies imparting the inhibition of the expression and activation of genes. Since said methods base on the sequence-specific hybridization of the inhibitory RNA molecules with respective target sequences in certain fungal genes, the expression of all corresponding genes from various fungi is thus inhibited as well. Due to the high sequence identity of such conserved gene sections, transgenic plants are thus produced, which have broad-spectrum resistance to various fungi.
Inventor(s): Schweizer; Patrick (Ballenstedt, DE), Hensel; Goetz (Koethen, DE), Gay; Alexandra (Odenthal, DE), Kumlehn; Jochen (Postdam, DE)
Assignee: The Leibniz Institute of Plant Genetics and Crop Plant Research (Gatersleben, DE)
Application Number:12/922,454
Patent Claims:see list of patent claims

Details for Patent 9,222,104

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Try a Free Trial The Leibniz Institute of Plant Genetics and Crop Plant Research (Gatersleben, DE) 2028-03-13 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Try a Free Trial The Leibniz Institute of Plant Genetics and Crop Plant Research (Gatersleben, DE) 2028-03-13 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Try a Free Trial The Leibniz Institute of Plant Genetics and Crop Plant Research (Gatersleben, DE) 2028-03-13 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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