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Last Updated: September 30, 2020

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Patent: 9,221,882

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Summary for Patent: 9,221,882
Title:Biosynthetic proline/alanine random coil polypeptides and their uses
Abstract: We discovered that a biosynthetic polypeptide, consisting of at least about 50 proline (Pro) and alanine (Ala) amino acid residues, forms a random coil, and increases the stability of other compounds to which it is conjugated, such as small molecules and polypeptides. We describe such biosynthetic polypeptides, constructs containing such polypeptides, ways of making them, and their use.
Inventor(s): Skerra; Arne (Freising, DE), Binder; Uli (Freising, DE), Schlapschy; Martin (Freising, DE)
Assignee: Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE)
Application Number:13/697,569
Patent Claims:see list of patent claims

Details for Patent 9,221,882

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE) 2030-05-21 RX search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE) 2030-05-21 RX search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE) 2030-05-21 RX search
Akorn Inc HYDASE hyaluronidase INJECTABLE;INJECTION 021716 001 2005-10-25   Start Trial Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE) 2030-05-21 DISCN search
Ekr Therap RETAVASE reteplase VIAL 103786 001 1998-05-06   Start Trial Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE) 2030-05-21 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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