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Last Updated: November 29, 2021

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Patent: 9,221,882

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Summary for Patent: 9,221,882
Title:Biosynthetic proline/alanine random coil polypeptides and their uses
Abstract: We discovered that a biosynthetic polypeptide, consisting of at least about 50 proline (Pro) and alanine (Ala) amino acid residues, forms a random coil, and increases the stability of other compounds to which it is conjugated, such as small molecules and polypeptides. We describe such biosynthetic polypeptides, constructs containing such polypeptides, ways of making them, and their use.
Inventor(s): Skerra; Arne (Freising, DE), Binder; Uli (Freising, DE), Schlapschy; Martin (Freising, DE)
Assignee: Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE)
Application Number:13/697,569
Patent Claims:see list of patent claims

Details for Patent 9,221,882

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-05-05 ⤷  Try it Free 2030-05-21
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-12-02 ⤷  Try it Free 2030-05-21
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 2004-10-26 ⤷  Try it Free 2030-05-21
Akorn, Inc. HYDASE hyaluronidase Injection 021716 2005-10-25 ⤷  Try it Free 2030-05-21
Chiesi Usa, Inc. RETAVASE reteplase For Injection 103786 1996-10-30 ⤷  Try it Free 2030-05-21
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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