Make Better Decisions - Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

Get the Book: Make Better Decisions

Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

PDF eBook: Just $10 Get Print Book on Amazon

Serving hundreds of leading biopharmaceutical companies globally:

US Army
Medtronic
Boehringer Ingelheim
McKesson
Chinese Patent Office
Cipla

Generated: September 23, 2019

DrugPatentWatch Database Preview

Patent: 9,211,315

  Try a free trial


See Plans and Pricing

« Back to Dashboard

Summary for Patent: 9,211,315
Title:Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
Abstract: The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active sHASEGP domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. Included are modified amino-terminal leader peptides that enhance secretion of sHASEGP. The invention further comprises sialated and pegylated form of a recombinant sHASEGP to enhance stability and serum pharmacokinetics over naturally occurring slaughterhouse enzymes. Further described are suitable formulations of a substantially purified recombinant sHASEGP glycoprotein derived from a eukaryotic cell that generate the proper glycosylation required for its optimal activity.
Inventor(s): Bookbinder; Louis H. (San Diego, CA), Kundu; Anirban (San Diego, CA), Frost; Gregory I. (Del Mar, CA)
Assignee: Halozyme, Inc. (San Diego, CA)
Application Number:14/120,224
Patent Claims:see list of patent claims

Details for Patent 9,211,315

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Cytogen PROSTASCINT capromab pendetide VIAL; INTRAVENOUS 103608 001 1996-10-28 ➤ Sign Up Halozyme, Inc. (San Diego, CA) 2023-03-05 RX search
Centocor Inc MYOSCINT imciromab pentetate VIAL 103634 001 1996-07-03 ➤ Sign Up Halozyme, Inc. (San Diego, CA) 2023-03-05 DISCN search
Novartis SIMULECT basiliximab VIAL; SINGLE-USE 103764 001 1998-05-12 ➤ Sign Up Halozyme, Inc. (San Diego, CA) 2023-03-05 RX search
Novartis SIMULECT basiliximab VIAL; SINGLE-USE 103764 002 1998-05-12 ➤ Sign Up Halozyme, Inc. (San Diego, CA) 2023-03-05 RX search
Medimmune SYNAGIS palivizumab VIAL 103770 001 1998-06-19 ➤ Sign Up Halozyme, Inc. (San Diego, CA) 2023-03-05 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

Make Better Decisions: Try a trial or see plans & pricing

Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
Cipla
Covington
Moodys
QuintilesIMS
Medtronic

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.