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Last Updated: December 1, 2021

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Patent: 9,198,966

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Summary for Patent: 9,198,966
Title:B-type plexin antagonists and uses thereof
Abstract: The present invention concerns the field of cancer therapy. In particular, it relates to an antagonist of a B-type plexin which prevents the interaction of the B-type plexin with ErbB-2 for use as a medicament, in particular, for treating metastasizing cancer. The present invention also contemplates a method for identifying an antagonist which prevents the interaction of a B-type plexin with ErbB-2. Finally, the invention provides for a polynucleotide encoding a B-type plexin polypeptide which lacks a functional intracellular domain and the said polypeptide.
Inventor(s): Offermanns; Stefan (Bad Nauheim, DE), Swiercz; Jakub (Bad Nauheim, DE), Worzfeld; Thomas (Bad Nauheim, DE)
Assignee: Ruprecht-Karls-Universitat Heidelberg (Heidelberg, DE) Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V. (Munich, DE)
Application Number:13/983,715
Patent Claims:see list of patent claims

Details for Patent 9,198,966

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 1998-09-25 ⤷  Try it Free 2031-02-09
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 2017-02-10 ⤷  Try it Free 2031-02-09
Genentech, Inc. AVASTIN bevacizumab Injection 125085 2004-02-26 ⤷  Try it Free 2031-02-09
Genentech, Inc. HERCEPTIN HYLECTA trastuzumab and hyaluronidase-oysk Injection 761106 2019-02-28 ⤷  Try it Free 2031-02-09
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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