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Last Updated: September 24, 2020

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Patent: 9,187,522

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Summary for Patent: 9,187,522
Title:GLP-1 receptor modulators
Abstract: The invention relates to compounds that modulate the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds are act as modulators or potentiators of GLP-1 receptor on their own, or with receptor ligands including GLP-1 peptides GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where \"\" represents either or both the R and S form of the compound): ##STR00001## where A, B, C, Y.sub.1, Y.sub.2, Z, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, W.sub.1, n, p and q are as defined herein.
Inventor(s): Boehm; Marcus F. (San Diego, CA), Martinborough; Esther (San Diego, CA), Moorjani; Manisha (San Diego, CA), Tamiya; Junko (Carlsbad, CA), Huang; Liming (San Diego, CA), Yeager; Adam R. (La Mesa, CA), Brahmachary; Enugurthi (San Diego, CA), Fowler; Thomas (Melton Mowbray, GB), Novak; Andrew (Nottingham, GB), Meghani; Premji (Leicestershire, GB), Knaggs; Michael (Burton-on-Trent, GB)
Assignee: Receptos, Inc. (San Diego, CA)
Application Number:14/296,907
Patent Claims:see list of patent claims

Details for Patent 9,187,522

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Glaxosmithkline Llc TANZEUM albiglutide INJECTABLE;INJECTION 125431 001 2014-04-15   Start Trial Receptos, Inc. (San Diego, CA) 2039-02-26 RX search
Sanofi-aventis Us ADLYXIN lixisenatide SOLUTION;SUBCUTANEOUS 208471 001 2016-07-27   Start Trial Receptos, Inc. (San Diego, CA) 2039-02-26 RX search
Sanofi-aventis Us ADLYXIN lixisenatide SOLUTION;SUBCUTANEOUS 208471 002 2016-07-27   Start Trial Receptos, Inc. (San Diego, CA) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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