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Last Updated: September 27, 2020

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Patent: 9,186,339

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Summary for Patent: 9,186,339
Title:Use of transcriptome modifying agents and chemotherapy or radiotherapy against cancer
Abstract: The use of transcriptome-modifying agents is disclosed in order to prevent malignant cells from undergoing the necessary genetic changes in order to combat cell insult and survive chemotherapy or radiotherapy. The combination of transcriptome-modifying agents comprises agents that inhibit the DNA methylation machinery plus a substance that inhibits histone deacetylation. A treatment kit is disclosed which includes an effective dose of hydralazine and valproic acid or a salt of same in the case of magnesium valproate, which is intended for use with radiotherapy or chemotherapy in the treatment of patients cancer.
Inventor(s): Gonzalez; Alfonso Duenas (Mexico D.F., MX), Flores; Luis Estrada (Col. Torielo Guerra, MX)
Assignee: UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (Mexico, C.P., Mexico City, unknown) PSICOFARMA, S.A. DE C.V. (Colonia Toriello Guerra, C.P., Mexico City, unknown)
Application Number:12/093,906
Patent Claims:see list of patent claims

Details for Patent 9,186,339

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (Mexico, C.P., Mexico City, unknown) PSICOFARMA, S.A. DE C.V. (Colonia Toriello Guerra, C.P., Mexico City, unknown) 2039-02-26 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (Mexico, C.P., Mexico City, unknown) PSICOFARMA, S.A. DE C.V. (Colonia Toriello Guerra, C.P., Mexico City, unknown) 2039-02-26 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (Mexico, C.P., Mexico City, unknown) PSICOFARMA, S.A. DE C.V. (Colonia Toriello Guerra, C.P., Mexico City, unknown) 2039-02-26 RX Orphan search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Start Trial UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (Mexico, C.P., Mexico City, unknown) PSICOFARMA, S.A. DE C.V. (Colonia Toriello Guerra, C.P., Mexico City, unknown) 2039-02-26 RX Orphan search
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (Mexico, C.P., Mexico City, unknown) PSICOFARMA, S.A. DE C.V. (Colonia Toriello Guerra, C.P., Mexico City, unknown) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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