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Generated: September 22, 2019

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Patent: 9,182,467

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Summary for Patent: 9,182,467
Title:Comparative analysis of protein conformations by using 2D NOESY NMR spectra
Abstract: The present disclosure provides a method for determining the relative conformations of a protein provided in different protein preparations, comprising steps of: (i) obtaining a first 2D NOESY NMR spectrum of a first protein preparation; (ii) obtaining a second 2D NOESY NMR spectrum of a second protein preparation; and (iii); determining whether a protein has a different conformation in the first and second protein preparations by comparing one or more cross-peaks in the first 2D NOESY NMR spectrum with one or more corresponding cross-peaks in the second 2D NOESY NMR spectrum.
Inventor(s): Parsons; Ian Christopher (Belmont, MA), Lansing; Jonathan (Reading, MA), Bosques; Carlos J. (Arlington, MA), Beccati; Daniela (Boston, MA)
Assignee: Momenta Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:12/595,867
Patent Claims:see list of patent claims

Details for Patent 9,182,467

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26   Try a Free Trial Momenta Pharmaceuticals, Inc. (Cambridge, MA) 2027-04-16 RX search
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Try a Free Trial Momenta Pharmaceuticals, Inc. (Cambridge, MA) 2027-04-16 RX Orphan search
Immunex ENBREL etanercept VIAL; SUBCUTANEOUS 103795 001 1998-11-02   Try a Free Trial Momenta Pharmaceuticals, Inc. (Cambridge, MA) 2027-04-16 RX Orphan search
Immunex ENBREL etanercept SYRINGE 103795 002 1998-11-02   Try a Free Trial Momenta Pharmaceuticals, Inc. (Cambridge, MA) 2027-04-16 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07   Try a Free Trial Momenta Pharmaceuticals, Inc. (Cambridge, MA) 2027-04-16 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07   Try a Free Trial Momenta Pharmaceuticals, Inc. (Cambridge, MA) 2027-04-16 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07   Try a Free Trial Momenta Pharmaceuticals, Inc. (Cambridge, MA) 2027-04-16 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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