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Generated: August 25, 2019

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Patent: 9,181,552

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Summary for Patent: 9,181,552
Title:Materials and methods directed to asparagine synthetase and asparaginase therapies
Abstract: Materials and Methods for use in treating cell proliferative disorders related to asparagine metabolism are provided. Cell proliferative disorders include such cancers as forms of leukemia, ovarian cancers, melanomas, renal cancers, breast cancers, brain cancers, and other cancers. Methods include the use of RNA interference targeted at asparagine synthetase to enhance the efficacy of L-asparaginase therapies.
Inventor(s): Lorenzi; Philip L. (Washington, DC), Weinstein; John N. (Chevy Chase, MD), Caplen; Natasha J. (Silver Spring, MD)
Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, DC)
Application Number:13/151,420
Patent Claims:see list of patent claims

Details for Patent 9,181,552

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Try a Free Trial The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, DC) 2026-03-03 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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