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Last Updated: June 3, 2020

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Patent: 9,173,939

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Summary for Patent: 9,173,939
Title:Ester derivatives of androgen receptor modulators and methods for their use
Abstract: Compounds having a structure of Structure I: ##STR00001## or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, J.sup.1, J.sup.2, X, Z, n.sup.1 and n.sup.2 are as defined herein, and wherein at least one of R.sup.1, R.sup.2 or R.sup.3 is an alkyl, alkenyl, aryl or aralkyl ester, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided.
Inventor(s): Andersen; Raymond J. (Vancouver, CA), Sadar; Marianne D. (Vancouver, CA), Fernandez; Javier Garcia (Gijon, CA), Mawji; Nasrin R. (Burnaby, CA), Wang; Jun (New Westminster, CA), Banuelos; Carmen Adriana (Vancouver, CA)
Assignee: The University of British Columbia (Vancouver, BC, CA) British Columbia Cancer Agency Branch (Vancouver, BC, CA)
Application Number:14/274,528
Patent Claims:see list of patent claims

Details for Patent 9,173,939

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial The University of British Columbia (Vancouver, BC, CA) British Columbia Cancer Agency Branch (Vancouver, BC, CA) 2033-05-10 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial The University of British Columbia (Vancouver, BC, CA) British Columbia Cancer Agency Branch (Vancouver, BC, CA) 2033-05-10 RX Orphan search
Bristol Myers Squibb YERVOY ipilimumab INJECTABLE; INJECTION 125377 001 2011-03-25   Start Trial The University of British Columbia (Vancouver, BC, CA) British Columbia Cancer Agency Branch (Vancouver, BC, CA) 2033-05-10 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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