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Last Updated: September 22, 2020

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Patent: 9,162,994

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Summary for Patent: 9,162,994
Title:1,2,4-thiazoloidin-3-one derivatives and their use in the treatment of cancer
Abstract: According to the invention there is provided a compound of formula (I) wherein: A represents C(.dbd.N--W-D) or S; B represents S or C(--NH--W-D); when: A represents C(.dbd.N--W-D) and B represents S then the bond between B and the NH atom is a single bond; or A represents S and B represents C(--NH--W-D) then the bond between B and the NH atom is a double bond; X represents -Q-[CR.sup.xR.sup.y].sub.n--; W represents --[CR.sup.xR.sup.y].sub.m-- or --C(O)--[CR.sup.xR.sup.y].sub.p--; Q represents a bond, --N(R.sup.a)--, --S--, or --O--; A.sub.1 to A.sub.5 respectively represent C(R.sup.1), C(R.sup.2), C(R.sup.3), C(R.sub.4) and C(R.sup.5), or, alternatively, up to two of A.sub.1 to A.sub.5 may independently represent N; D represents phenyl, pyridyl or pyrimidinyl optionally substituted by one or more R.sup.6 groups, which compounds are useful in the treatment of cancer.
Inventor(s): Westman; Jacob (Blomsberg, SE), Hallett; Allan (Welwyn Garden City, GB), Vagberg; Jan (Sollentuna, SE)
Assignee: BETAGENON AB (Umea, SE)
Application Number:13/381,426
Patent Claims:see list of patent claims

Details for Patent 9,162,994

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial BETAGENON AB (Umea, SE) 2039-02-26 RX Orphan search
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial BETAGENON AB (Umea, SE) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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