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Last Updated: September 30, 2020

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Patent: 9,132,281

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Summary for Patent: 9,132,281
Title:Focused radiation for augmenting immune-based therapies against neoplasms
Abstract: An approach combining immune-based therapies with focused radiation, including stereotactic radiation, to treat cancers is disclosed. The use of focused radiation primes the immune system in a similar manner to vaccines to augment immune-based therapies and can counteract the suppressive effects of a tumor. The combination of focused radiation and immune-based therapies, including administration of at least one immunotherapeutic agent, improves survival compared to each therapy alone and can, in some cases, lead to a durable cure. Accordingly, focused radiation can be an adjuvant for immune-based therapies for treating cancers.
Inventor(s): Zeng; Jing (Rockville, MD), Drake; Charles George (Baltimore, MD), Pardoll; Drew M. (Brookeville, MD), Lim; Michael (Reisterstown, MD)
Assignee: The Johns Hopkins University (Baltimore, MD)
Application Number:14/127,597
Patent Claims:see list of patent claims

Details for Patent 9,132,281

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bristol Myers Squibb YERVOY ipilimumab INJECTABLE; INJECTION 125377 001 2011-03-25   Start Trial The Johns Hopkins University (Baltimore, MD) 2031-06-21 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Boehringer Ingelheim
Harvard Business School

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