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Generated: July 15, 2019

DrugPatentWatch Database Preview

Patent: 9,132,113

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Summary for Patent: 9,132,113
Title:Compositions and methods of use of phorbol esters
Abstract: Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of cytopathic diseases. Cytopathic diseases may be caused by a variety means such as viral infections like HIV and AIDS in a mammalian subject. The methods and compositions of the invention are effective for inhibiting de novo HIV infection, upregulating viral expression from latent provirus, inhibiting HIV-induced cytopathic effects, down regulating the HIV receptor, increasing ThI cytokine expression, and decreasing Th2 cytokine expression. Additional compositions and methods are provided which employ a phorbol ester or derivative compound in combination with at least one additional agent such as those used in HAART protocols or therapeutic agents used to treat opportunistic infections due to HIV in mammalian subjects.
Inventor(s): Han; Zheng Tao (Zhengzhou, CN), Chang; Richard L. (Pinebrook, NJ)
Assignee: BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA)
Application Number:13/794,467
Patent Claims:see list of patent claims

Details for Patent 9,132,113

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Chiron PROLEUKIN aldesleukin VIAL 103293 001 1992-05-05 ➤ Sign Up BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA) ➤ Sign Up RX search
Amgen EPOGEN/PROCRIT epoetin alfa VIAL; SINGLE-USE 103234 007 1989-06-01 ➤ Sign Up BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA) ➤ Sign Up RX search
Amgen EPOGEN/PROCRIT epoetin alfa VIAL; SINGLE-USE 103234 006 1989-06-01 ➤ Sign Up BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA) ➤ Sign Up RX search
Amgen EPOGEN/PROCRIT epoetin alfa VIAL; SINGLE-USE 103234 005 1989-06-01 ➤ Sign Up BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA) ➤ Sign Up RX search
Amgen EPOGEN/PROCRIT epoetin alfa VIAL; SINGLE-USE 103234 004 1989-06-01 ➤ Sign Up BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA) ➤ Sign Up RX search
Amgen EPOGEN/PROCRIT epoetin alfa VIAL; MULTIDOSE 103234 003 1989-06-01 ➤ Sign Up BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 9,132,113

Country Patent Number Publication Date
South Africa 200905273 Apr 28, 2010
South Africa 201405564 Feb 24, 2016
South Africa 201508059 Dec 21, 2016
World Intellectual Property Organization (WIPO) 2008094657 Aug 07, 2008
World Intellectual Property Organization (WIPO) 2013110006 Feb 05, 2015
World Intellectual Property Organization (WIPO) 2013110006 Jul 25, 2013
Country Patent Number Publication Date

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