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Last Updated: December 8, 2021

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Patent: 9,132,113

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Summary for Patent: 9,132,113
Title:Compositions and methods of use of phorbol esters
Abstract: Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of cytopathic diseases. Cytopathic diseases may be caused by a variety means such as viral infections like HIV and AIDS in a mammalian subject. The methods and compositions of the invention are effective for inhibiting de novo HIV infection, upregulating viral expression from latent provirus, inhibiting HIV-induced cytopathic effects, down regulating the HIV receptor, increasing ThI cytokine expression, and decreasing Th2 cytokine expression. Additional compositions and methods are provided which employ a phorbol ester or derivative compound in combination with at least one additional agent such as those used in HAART protocols or therapeutic agents used to treat opportunistic infections due to HIV in mammalian subjects.
Inventor(s): Han; Zheng Tao (Zhengzhou, CN), Chang; Richard L. (Pinebrook, NJ)
Assignee: BIOSUCCESS BIOTECH COMPANY (Los Angeles, CA)
Application Number:13/794,467
Patent Claims:see list of patent claims

Details for Patent 9,132,113

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1987-06-23 ⤷  Free Forever Trial 2027-01-31
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1986-10-16 ⤷  Free Forever Trial 2027-01-31
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1999-02-04 ⤷  Free Forever Trial 2027-01-31
Emd Serono, Inc. SAIZEN somatropin For Injection 019764 1996-10-08 ⤷  Free Forever Trial 2027-01-31
Emd Serono, Inc. SAIZEN somatropin For Injection 019764 2000-08-29 ⤷  Free Forever Trial 2027-01-31
Emd Serono, Inc. SAIZEN somatropin For Injection 019764 2007-01-16 ⤷  Free Forever Trial 2027-01-31
Ferring Pharmaceuticals Inc. ZOMACTON somatropin For Injection 019774 1995-05-25 ⤷  Free Forever Trial 2027-01-31
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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