Upgrade for Complete Access See Plans and Pricing

Serving leading biopharmaceutical companies globally:

Express Scripts

Last Updated: December 1, 2021

DrugPatentWatch Database Preview

Patent: 9,125,743

➤ Subscribe for complete access

« Back to Dashboard

Summary for Patent: 9,125,743
Title:Devitalization and recellularization of cartilage
Abstract: The present invention is directed toward recellularizing a devitalized cartilage graft with viable recellularizable cells in vivo, in situ, or in vitro to render the tissue vital. The present invention is also directed toward repairing a cartilage defect and implanting a cartilage graft into a human or animal by crafting a cartilage matrix into individual grafts, disinfecting and cleaning the cartilage graft, applying a pretreatment solution to the cartilage graft, removing cellular debris using an extracting solution to produce a devitalized cartilage graft, recellularizing the devitalized cartilage graft, implanting the cartilage graft into the cartilage defect with or without an insertion device, and sealing the implanted cartilage graft with recipient tissue. The devitalized cartilage graft is optionally stored between the removing cellular debris and the recellularizing steps. The present invention is directed to both recellularized cartilage grafts as well as a process for recellularizing cartilage grafts.
Inventor(s): Chen; Silvia Sihui (Derwood, MD), Qin; Xiaofei (Virginia Beach, VA), Chen; Jingsong (Virginia Beach, VA), Wolfinbarger; Lloyd (Norfolk, VA), Moore; Mark (Chesapeake, VA), Thomas; Rony (Virginia Beach, VA), Linthurst Jones; Alyce (Virginia Beach, VA)
Assignee: LifeNet Health (Virginia Beach, VA)
Application Number:11/826,523
Patent Claims:see list of patent claims

Details for Patent 9,125,743

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-05-05 ⤷  Try it Free 2039-02-26
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-12-02 ⤷  Try it Free 2039-02-26
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 2004-10-26 ⤷  Try it Free 2039-02-26
Akorn, Inc. HYDASE hyaluronidase Injection 021716 2005-10-25 ⤷  Try it Free 2039-02-26
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Harvard Business School

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.