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Last Updated: December 3, 2021

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Patent: 9,109,010

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Summary for Patent: 9,109,010
Title:Viral inactivation during purification of antibodies cross reference to related applications
Abstract: Described herein are methods for isolating and purifying antibodies from a sample matrix. One aspect of the present disclosure is directed to viral reduction/inactivation of samples generated in the various steps of antibody purification. In a particular aspect, methods herein employ an acidification step followed by one or more chromatography steps. The chromatography steps can include one or more of the following chromatographic procedures: ion exchange chromatography, affinity chromatography, and hydrophobic interaction chromatography.
Inventor(s): Hickman; Robert K. (Worcester, MA), Correia; Ivan R. (Winchester, MA)
Assignee: AbbVie Inc. (North Chicago, IL)
Application Number:12/582,556
Patent Claims:see list of patent claims

Details for Patent 9,109,010

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 2002-12-31 ⤷  Try it Free 2028-10-20
Abbvie Inc. HUMIRA adalimumab Injection 125057 2008-02-21 ⤷  Try it Free 2028-10-20
Abbvie Inc. HUMIRA adalimumab Injection 125057 2013-04-24 ⤷  Try it Free 2028-10-20
Abbvie Inc. HUMIRA adalimumab Injection 125057 2014-09-23 ⤷  Try it Free 2028-10-20
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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