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Last Updated: September 21, 2020

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Patent: 9,101,559

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Summary for Patent: 9,101,559
Title:Leukemic cell CNS infiltration controlled by notch-induced chemotaxis
Abstract: The present invention is directed to methods of preventing central nervous system leukemia, treating T-cell acute lymphoblastic leukemia, and treating immune system disorders associated with CCR7-CCL19 mediated signaling. Suitable therapeutic agents for inhibiting CCR7-CCL19 signaling and methods of identifying additional therapeutic agents useful in the methods of the present invention are also disclosed.
Inventor(s): Aifantis; Iannis (Brooklyn, NY), Buonamici; Silvia (Boston, MA)
Assignee: New York University (New York, NY)
Application Number:12/776,920
Patent Claims:see list of patent claims

Details for Patent 9,101,559

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial New York University (New York, NY) 2029-05-08 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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