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Last Updated: November 27, 2021

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Patent: 9,096,907

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Summary for Patent: 9,096,907
Title:Prostate cancer prognostic compositions and kits
Abstract: Described herein are method, compositions and kits for prognosis of prostate cancer. The methods include determining the ratio of PCA3 and of a prostate-specific marker expression in a urine sample and correlating the value of the PCA3/prostate-specific marker ratio with the aggressiveness and mortality risk of prostate cancer in the subject. The method for prognosing prostate cancer in a sample of a patient includes assessing the amount of a prostate cancer specific PCA3 mRNA and the amount of prostate-specific marker in the sample; determining a ratio value of this amount of prostate cancer specific PCA3 mRNA over the amount of prostate-specific marker; comparing the ratio value to at least one predetermined cut-off value, wherein a ratio value above the predetermined cut-off value is indicative of a higher risk of mortality of prostate cancer as compared to a ratio value below the predetermined cut-off value.
Inventor(s): Hessels; Daphne (Malden, NL), Verhaegh; Gerald (Maden, NL), Schalken; Jack A. (Nijmegen, NL), Witjes; J. Alfred (Nijmegen, NL)
Assignee: Stichting Katholieke Universiteit, The University Medical Centre Nijmegen (Nijmegen, NL)
Application Number:13/914,303
Patent Claims:see list of patent claims

Details for Patent 9,096,907

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2024-12-24
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2024-12-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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