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Last Updated: September 21, 2020

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Patent: 9,090,945

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Summary for Patent: 9,090,945
Title:Mean DNA copy number of chromosomal regions is of prognostic significance in cancer
Abstract: Methods for predicting a disease free time interval (DFI) for a cancer patient under consideration for initial or further chemotherapy treatment are disclosed. The methods include obtaining a biological sample from a patient and detecting a copy number of chromosome region A1 and/or C2. The mean copy number per cell is correlated with a DFI for the subject. The chemotherapy can include doxorubicin and/or L-asparaginase treatment. Also provided are kits for predicting DFI in a subject with cancer and computer readable storage media for performing the presently disclosed methods.
Inventor(s): Breen; Matthew (Apex, NC)
Assignee: North Carolina State University (Raleigh, NC)
Application Number:13/515,614
Patent Claims:see list of patent claims

Details for Patent 9,090,945

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial North Carolina State University (Raleigh, NC) 2039-03-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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