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Last Updated: November 27, 2021

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Patent: 9,078,881

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Summary for Patent: 9,078,881
Title:Salinosporamides and methods of use thereof
Abstract: The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian cells. The CNB392 and CNB476 strains lie within the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by this strain are classified as salinosporamides, and are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC.sub.50 values, high pharmaceutical potency, and selectivity for cancer cells over fungi.
Inventor(s): Fenical; William (Del Mar, CA), Jensen; Paul (San Diego, CA), Mincer; Tracy (San Diego, CA), Feling; Robert H. R. (Wiesbaden, DE)
Assignee: The Regents of the University of California (Oakland, CA)
Application Number:14/139,692
Patent Claims:see list of patent claims

Details for Patent 9,078,881

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 1978-01-10 ⤷  Try it Free 2022-06-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Boehringer Ingelheim

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